Annexin a1 anticorps
Aperçu rapide pour Annexin a1 anticorps (ABIN498466)
Antigène
Voir toutes Annexin a1 (ANXA1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- This antibody detects endogenous levels of Annexin I protein. (region surrounding asn146)
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Réactivité croisée (Details)
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
Purification
- Affinity chromatography
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Pureté
- > 95 % by SDS-PAGE
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Indications d'application
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Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1,0 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH 7.2.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Annexin a1 (ANXA1) (Annexin A1 (ANXA1))
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Autre désignation
- Annexin A1 / ANXA1
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Sujet
- During apoptosis, phosphatidylserine (PS) is translocated from the cytoplasmic face of the plasma membrane to the cell surface. Annexin V has a strong, Ca2+-dependent affinity for PS and therefore is used as a probe for detecting apoptosis. Annexin V has also been identified as an anticoagulant protein in the blood coagulation cascade, by acting as an inhibitor of prothrombin activation. The presence of antibodies to Annexin V is associated with systemic lupus erythematosus (SLE), recurrent spontaneous abortions and systemic sclerosis (SSc).Synonyms: ANX1, Annexin I, Annexin-1, Calpactin II, Chromobindin-9, LPC1, Lipocortin I, Phospholipase A2 inhibitory protein, p35
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Poids moléculaire
- approx. 39 kDa
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ID gène
- 301
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NCBI Accession
- NP_000691
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UniProt
- P04083
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Pathways
- Hormone Transport
Antigène
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