IL20RA anticorps

N° du produit ABIN498494

Détail du produit anti-IL20RA anticorps

Antigène: IL20RA (Interleukin 20 Receptor alpha (IL20RA))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL20RA est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects endogenous levels of IL-20Ralpha protein. (region surrounding Val222)

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Affinity Chromatography using epitope-specific immunogen.

Information d'application

Indications d'application: Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur IL20RA

Antigène: IL20RA (Interleukin 20 Receptor alpha (IL20RA))

Autre désignation: IL20RA (IL20RA Produits)

Synonymes: anticorps CRF2-8, anticorps IL-20R-alpha, anticorps IL-20R1, anticorps IL-20RA, anticorps E230031K19, anticorps interleukin 20 receptor subunit alpha, anticorps interleukin 20 receptor, alpha, anticorps IL20RA, anticorps Il20ra

Sujet: The class II cytokine receptor family includes 12 members, 11 of which combine as various heterodimers to transduce signals across the cellular membrane for 27 cytokines. These cytokines are divided into four structurally related groups: six cytokines of the IL-10 family, 17 type I IFNs, one type II IFN and three IFN-lambda. IL-20 is a member of the IL-10 family of cytokines that has been shown to be upregulated in psoriatic skin. The receptor for IL-20 (IL-20R) exists as a dimer consisting of IL-20Ralpha and IL-20Rbeta. IL-20R also functions as a receptor for IL-19, IL-24 and IL-26. It is highly expressed in skin, brain and testis. IL-20, IL-20Ralpha and IL-20Rbeta all have higher expression levels in psoriatic lesional (LS) skin than in nonlesional (NL) skin, suggesting a role for these proteins as potential therapeutic targets. IL-20 can induce signal transducer and activator of transcription (Stat) activation through IL-20R.Synonyms: Cytokine receptor class-II member 8, Cytokine receptor family 2 member 8, IL-20R-alpha, IL-20R1, Interleukin-20 receptor alpha chain, ZCYTOR7

Poids moléculaire: approx. 62 kDa

ID gène: 53832

NCBI Accession: NP_055247

UniProt: Q9UHF4