Cholecystokinin anticorps

N° du produit ABIN498541

Cet anticorps Lapin Polyclonal détecte spécifiquement Cholecystokinin dans IHC (p). Il présente une réactivité avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour Cholecystokinin anticorps (ABIN498541)

Antigène: Cholecystokinin (CCK)

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cholecystokinin est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Cholecystokinin anticorps

Specificité: This antibody detects endogenous levels of CCK protein. (region surrounding Val46)

Réactivité croisée (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Affinity Chromatography using epitope-specific immunogen

Information d'application

Indications d'application: Immunohistochemistry on paraffin sections: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Cholecystokinin

Antigène: Cholecystokinin (CCK)

Autre désignation: Cholecystokinin / CCK

Sujet: CCK (cholecystokinin) is a 115 amino acid secreted protein belonging to the gastrin/cholecystokinin family. CCK has been shown to stimulate the growth of pancreatic cancer. As a peptide hormone, CCK induces gallbladder contraction and the release of pancreatic enzymes in the gut. Binding of CCK to CCK-A receptors stimulates amylase release from the pancreas, while binding to CCK-B receptors stimulates gastric acid secretion. The function of CCK in the brain is not clear. The CCK precursor is cleaved by proteases to produce a number of active cholecystokinins including CCK58, CCK58 desnonopeptide, CCK39, CCK33, CCK25, CCK18, CCK12, CCK8, CCK7 and CCK5.

Poids moléculaire: approx. 13 kDa

ID gène: 885

NCBI Accession: NP_000720

UniProt: P06307

Pathways: TCR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades, Feeding Behaviour