Cholecystokinin anticorps

N° du produit ABIN498541

Détail du produit anti-Cholecystokinin anticorps

Antigène: Cholecystokinin (CCK)

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cholecystokinin est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects endogenous levels of CCK protein. (region surrounding Val46)

Réactivité croisée (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Affinity Chromatography using epitope-specific immunogen

Information d'application

Indications d'application: Immunohistochemistry on paraffin sections: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Cholecystokinin

Antigène: Cholecystokinin (CCK)

Autre désignation: Cholecystokinin / CCK (CCK Produits)

Synonymes: anticorps CCK, anticorps CCK-CH, anticorps cck-a, anticorps cck-b, anticorps cholecystokinin, anticorps cholecystokinin L homeolog, anticorps CCK, anticorps Cck, anticorps cck, anticorps cck.L

Sujet: CCK (cholecystokinin) is a 115 amino acid secreted protein belonging to the gastrin/cholecystokinin family. CCK has been shown to stimulate the growth of pancreatic cancer. As a peptide hormone, CCK induces gallbladder contraction and the release of pancreatic enzymes in the gut. Binding of CCK to CCK-A receptors stimulates amylase release from the pancreas, while binding to CCK-B receptors stimulates gastric acid secretion. The function of CCK in the brain is not clear. The CCK precursor is cleaved by proteases to produce a number of active cholecystokinins including CCK58, CCK58 desnonopeptide, CCK39, CCK33, CCK25, CCK18, CCK12, CCK8, CCK7 and CCK5.

Poids moléculaire: approx. 13 kDa

ID gène: 885

NCBI Accession: NP_000720

UniProt: P06307

Pathways: TCR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades, Feeding Behaviour