MARCKS anticorps

N° du produit ABIN498653

Détail du produit anti-MARCKS anticorps

Antigène: MARCKS (Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MARCKS est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects endogenous levels of MARCKS protein. (region surrounding Arg157)

Réactivité croisée (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Pureté: > 95 % by SDS-PAGE

Information d'application

Indications d'application: Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur MARCKS

Antigène: MARCKS (Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS))

Autre désignation: MARCKS (MARCKS Produits)

Synonymes: anticorps 80K-L, anticorps MACS, anticorps PKCSL, anticorps PRKCSL, anticorps KINC, anticorps Macs, anticorps marcks, anticorps MGC89127, anticorps MARCKS, anticorps macs, anticorps wu:fb55c06, anticorps wu:fb92d04, anticorps wu:fc19b04, anticorps wu:fc44a10, anticorps zgc:110235, anticorps fc34g03, anticorps fc38c06, anticorps wu:fc34g03, anticorps wu:fc38c06, anticorps zgc:109978, anticorps myristoylated alanine rich protein kinase C substrate, anticorps myristoylated alanine-rich protein kinase C substrate, anticorps methyl binding domain106, anticorps myristoylated alanine-rich protein kinase C substrate b, anticorps myristoylated alanine-rich protein kinase C substrate S homeolog, anticorps myristoylated alanine-rich protein kinase C substrate a, anticorps MARCKS, anticorps Marcks, anticorps marcks, anticorps mbd106, anticorps marcksb, anticorps marcks.S, anticorps marcksa

Sujet: Myristoylated alanine-rich protein kinase C substrate (MARCKS), also designated 80K or 80K-L, has been identified as a major cellular substrate for protein kinase C. Human MARCKS is a 332 amino acid protein with a calculated molecular weight of 31.534 kDa, however, it has been shown to run at 80-87 kDa on Western blot. The plasma membrane bound protein dissociates from the membrane upon phosphorylation by various PKC isoforms. In NIH/3T3 fibroblasts, PKC alpha and PKC epsilon, but not PKC delta, are responsible for MARCKS phosphorylation. MARCKS has been found to bind calmodulin, Actin and Synapsin and is a filamentous (F) Actin crosslinking protein.Synonyms: MACS, Myristoylated alanine-rich C-kinase substrate, PRKCSL

Poids moléculaire: approx. 32, 75, 87 kDa

ID gène: 4082

NCBI Accession: NP_002347

UniProt: P29966