Decorin anticorps (Internal Region)

N° du produit ABIN499170

Détail du produit anti-Decorin anticorps

Antigène: Decorin (DCN)

Épitope: Internal Region

Reactivité: Humain, Boeuf (Vache), Cobaye, Porc

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp Decorin est non-conjugé

Application: Western Blotting (WB)

Séquence: C-KISRVDAASL KGLNN

Specificité: This antibody detects Decorin (Internal). It is expected to recognize the three reported isoforms a, b and c (NP_001911.1, NP_598011.1, NP_598012.1 resp.). Reported variants NP_598010.1 and NP_001911.1 represent identical protein.

Réactivité croisée (Details): Species reactivity (expected):Cow, pig, caviaSpecies reactivity (tested):Human

Purification: Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Immunogène: Peptide from the internal region of the protein sequence according to NP_001911.1, NP_598011.1, NP_598012.1

Information d'application

Indications d'application: Peptide ELISA: limit dilution 1: 8000. Western blot: 0.5-2 μg/mL. Approx 38 kDa band observed in Human Kidney lysates(calculated MW of 39.8 kDa according to NP_001911.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C up to one week or (in aliquots) at -20 °C for longer.

Détails sur Decorin

Antigène: Decorin (DCN)

Autre désignation: Decorin (DCN Produits)

Synonymes: anticorps CSCD, anticorps DSPG2, anticorps PG40, anticorps PGII, anticorps PGS2, anticorps SLRR1B, anticorps DC, anticorps mDcn, anticorps cscd, anticorps dspg2, anticorps pg40, anticorps pgii, anticorps pgs2, anticorps slrr1b, anticorps decorin, anticorps decorin L homeolog, anticorps DCN, anticorps Dcn, anticorps dcn.L, anticorps dcn

Sujet: Decorin is a member of the small, leucine rich proteoglycan (SLRP) family along with biglycan. Found in the interterritorial region of cartilage, decorin interacts with collagen and other matrix proteins to regulate the cartilaginous matrix. It has been shown to interact with fibronectin, thrombospondin, C1q, epidermal growth factor receptor (EGFR), and TGF beta. It is believed that decorin also plays a role in the cell cycle of chondrocytes.Synonyms: Bone proteoglycan II, DCN, PG-S2, PG40, SLRR1B

ID gène: 1634

NCBI Accession: NP_001911

UniProt: P07585

Pathways: Glycosaminoglycan Metabolic Process