Aconitase 1 anticorps (Internal Region)

N° du produit ABIN499173

Détail du produit anti-Aconitase 1 anticorps

Antigène: Aconitase 1 (ACO1)

Épitope: Internal Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache)

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp Aconitase 1 est non-conjugé

Application: Western Blotting (WB)

Séquence: C-QVDFNRRADS LQKNQ

Specificité: This antibody detects ACO1 / IREB1 (Internal).

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat, Cow.
Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogène: Peptide from the internal region of the protein sequence according to NP_002188.1 Genename: ACO1

Information d'application

Indications d'application: Peptide ELISA: 1: 8000 (limit dilution). Western blot: 0.1-0.3 μg/mL. Approx 100 kDa band observed in Human Liver lysates(calculated MW of 98.0 kDa according to NP_002188.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 containing 0.02 % Sodium Azide and 0.5 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C

Stockage commentaire: Store the antibody at 2-8 °C for one week or (in aliquots) at -20 °C for longer.

Détails sur Aconitase 1

Antigène: Aconitase 1 (ACO1)

Autre désignation: ACO1 / IREB1 (ACO1 Produits)

Synonymes: anticorps ACONS, anticorps IREB1, anticorps IREBP, anticorps IREBP1, anticorps IRP1, anticorps Acon1, anticorps Ratireb, anticorps ratireb, anticorps Aco1, anticorps AI256519, anticorps Aco-1, anticorps Irebp, anticorps Irp1, anticorps aconitase 1, anticorps aconitase 1, soluble, anticorps aconitase 1 L homeolog, anticorps ACO1, anticorps Aco1, anticorps aco1.L

Sujet: Aconitase 1 (ACO1) also known as iron regulatory element binding protein 1 (IREB1), is a cytosolic protein which binds to iron-responsive elements (IRES). IREs are translational regulatory sequences found in the 5'-UTR of ferritin, and in the 3'-UTR of transferrin receptor mRNA. Thus, IREB1 plays a central role in cellular iron homeostasis by regulating ferritin mRNA translation and TFRC mRNA stability.Synonyms: Aconitase, Citrate hydro-lyase, Cytoplasmic aconitate hydratase, Ferritin repressor protein, IRP1, Iron regulatory protein 1, Iron-responsive element-binding protein 1

ID gène: 48

NCBI Accession: NP_002188

UniProt: P21399

Pathways: Transition Metal Ion Homeostasis