BID anticorps (Middle Region)
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- Antigène Voir toutes BID Anticorps
- BID (BH3 Interacting Domain Death Agonist (BID))
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Épitope
- Middle Region
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp BID est non-conjugé
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Specificité
- Bid antibody was raised against a peptide corresponding to 14 amino acids near the middle of human Bid.
- Purification
- Ion exchange chromatography
- Immunogène
- Human Bid (IN) Peptide
- Isotype
- IgG
- Top Product
- Discover our top product BID Anticorps primaire
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- Indications d'application
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ELISA. Western Blot: Bid antibody can be used for detection of Bid at 1 to 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Buffer
- PBS containing 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C.
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- Antigène
- BID (BH3 Interacting Domain Death Agonist (BID))
- Autre désignation
- BID (BID Produits)
- Synonymes
- anticorps FP497, anticorps 2700049M22Rik, anticorps AI875481, anticorps AU022477, anticorps BID, anticorps bid, anticorps si:ch211-238n5.6, anticorps fp497, anticorps xbid, anticorps DKFZp469E066, anticorps BH3 interacting domain death agonist, anticorps BH3 interacting domain death agonist S homeolog, anticorps BID, anticorps Bid, anticorps bida, anticorps bid.S, anticorps bid
- Sujet
- Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer (reviewed in 1). The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death (reviewed in 2 and 3). Bid, a pro-apoptotic Bcl-2 family member, is cleaved by caspase-8 in response to apoptotic signals (4,5), exposing the Bcl-2 homology 3 (BH3) domain which is normally buried in the full-length protein (6). The cleaved complex is myris-toylated and translocated to the mitochondrial membrane where it may induce mitochondrial Bax and Bak to oligomerize (7,8).Synonyms: BH3-interacting domain death agonist, p22 BID
- ID gène
- 637
- UniProt
- P55957
- Pathways
- Apoptose, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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