BRSK2 anticorps (C-Term)

N° du produit ABIN499503

Cet anticorps anti-BRSK2 est un anticorps Lapin Polyclonal détectant BRSK2 dans WB, IHC (p) et EIA. Adapté pour Humain et Souris.

Aperçu rapide pour BRSK2 anticorps (C-Term) (ABIN499503)

Antigène: BRSK2 (BR serine/threonine Kinase 2 (BRSK2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BRSK2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-BRSK2 anticorps

Épitope: C-Term

Specificité: This antibody reacts to BRSK2.

Purification: Affinity chromatography purified via peptide column

Immunogène: BRSK2 antibody was raised against a 23 amino acid peptide from near the carboxy terminus of human BRSK2.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: BRSK2 antibody can be used for detection of BRSK2 at 1 - 2 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur BRSK2

Antigène: BRSK2 (BR serine/threonine Kinase 2 (BRSK2))

Autre désignation: BRSK2

Sujet: BRSK2 was initially identified through a computer screen of the human genome and shows significant homology to the C. elegans neuronal cell polarity regulator SAD1. BRSK2 is expressed in the brain and to a lesser extent in the testes. BRSK2 is a member of the AMP-activated protein kinase subfamily and can be activated by the tumor suppressor kinase LKB1. More recently, it has been shown that both BRSK2 and the related protein BRSK1 are required for mammalian neuronal polarization. While BRSK1- and BRSK2-null mice were viable, double-mutant mice died within two hours of birth. Neurons from these mice showed uniformly-sized neurites as opposed to the normal long axon and multiple shorter dendrites. These neurites also displayed both axonal and dendritic markers. BRSK2 has also been shown to be an autoantigen in paraneoplastic limbic encephalitis. At least four isoforms of BRSK2 are known to exist.Synonyms: BR serine/threonine-protein kinase 2, C11orf7, HUSSY-12, PEN11B, SAD-A, STK29, Serine/threonine kinase SAD-A, Serine/threonine-protein kinase 29

ID gène: 9024

UniProt: Q8IWQ3