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BRSK2 anticorps (C-Term)

BRSK2 Reactivité: Humain, Souris WB, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN499503
  • Antigène Voir toutes BRSK2 Anticorps
    BRSK2 (BR serine/threonine Kinase 2 (BRSK2))
    Épitope
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    C-Term
    Reactivité
    • 23
    • 20
    • 2
    Humain, Souris
    Hôte
    • 30
    • 2
    • 1
    Lapin
    Clonalité
    • 33
    Polyclonal
    Conjugué
    • 11
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp BRSK2 est non-conjugé
    Application
    • 24
    • 22
    • 7
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificité
    This antibody reacts to BRSK2.
    Purification
    Affinity chromatography purified via peptide column
    Immunogène
    BRSK2 antibody was raised against a 23 amino acid peptide from near the carboxy terminus of human BRSK2.
    Isotype
    IgG
    Top Product
    Discover our top product BRSK2 Anticorps primaire
  • Indications d'application
    ELISA. Western Blot: BRSK2 antibody can be used for detection of BRSK2 at 1 - 2 μg/mL. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C.
  • Antigène
    BRSK2 (BR serine/threonine Kinase 2 (BRSK2))
    Autre désignation
    BRSK2 (BRSK2 Produits)
    Synonymes
    anticorps C11orf7, anticorps PEN11B, anticorps SAD1, anticorps SADA, anticorps STK29, anticorps BRSK2, anticorps 4833424K13Rik, anticorps SAD-A, anticorps BR serine/threonine kinase 2, anticorps BRSK2, anticorps Brsk2
    Sujet
    BRSK2 was initially identified through a computer screen of the human genome and shows significant homology to the C. elegans neuronal cell polarity regulator SAD1. BRSK2 is expressed in the brain and to a lesser extent in the testes. BRSK2 is a member of the AMP-activated protein kinase subfamily and can be activated by the tumor suppressor kinase LKB1. More recently, it has been shown that both BRSK2 and the related protein BRSK1 are required for mammalian neuronal polarization. While BRSK1- and BRSK2-null mice were viable, double-mutant mice died within two hours of birth. Neurons from these mice showed uniformly-sized neurites as opposed to the normal long axon and multiple shorter dendrites. These neurites also displayed both axonal and dendritic markers. BRSK2 has also been shown to be an autoantigen in paraneoplastic limbic encephalitis. At least four isoforms of BRSK2 are known to exist.Synonyms: BR serine/threonine-protein kinase 2, C11orf7, HUSSY-12, PEN11B, SAD-A, STK29, Serine/threonine kinase SAD-A, Serine/threonine-protein kinase 29
    ID gène
    9024
    UniProt
    Q8IWQ3
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