BUB3 anticorps (C-Term, N-Term)

N° du produit ABIN499513

Cet anticorps Lapin Polyclonal détecte spécifiquement BUB3 dans WB, IF et EIA. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour BUB3 anticorps (C-Term, N-Term) (ABIN499513)

Antigène: BUB3 (Budding Uninhibited By Benzimidazoles 3 Homolog (Yeast) (BUB3))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BUB3 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Détail du produit anti-BUB3 anticorps

Épitope: C-Term, N-Term

Specificité: This antibody reacts to Bub3.

Purification: Affinity chromatography purified via peptide column

Immunogène: Bub3 antibody was raised against a 16 amino acid peptide from near the carboxy terminus of human bub3.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: Bub3 antibody can be used for detection of bub3 at 0.5 μg/mL. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur BUB3

Antigène: BUB3 (Budding Uninhibited By Benzimidazoles 3 Homolog (Yeast) (BUB3))

Autre désignation: BUB3

Sujet: The mitotic checkpoint protein Bub3 is involved with the essential spindle checkpoint pathway which operates during early embryogenesis. Bub3 is important during G2 and early mitosis stages, permitting entry into mitosis depending upon the assembly state of microtubules, thus preventing premature sister chromatid separation, mis-segregation and aneuploidy. Bub3 contains four WD repeat domains and is required for the kinetochore localization of Bub1, a related kinase that is necessary for spindle assembly checkpoint function. Bub1 is able to autophosphorylate and can catalyze the phosphorylation of Bub3. Both Bub1 and Bub3 are mutually dependent for function. Altered Bub expression levels may significantly impair mitotic checkpoint function and is associated with tumor cell proliferation.Synonyms: Mitotic checkpoint protein BUB3

ID gène: 9184

UniProt: O43684

Pathways: Maintenance of Protein Location