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CASP5 anticorps (Intermediate Domain)

CASP5 Reactivité: Humain WB, IF, EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN499567
  • Antigène Voir toutes CASP5 Anticorps
    CASP5 (Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5))
    Épitope
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Intermediate Domain
    Reactivité
    • 43
    • 8
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 40
    • 3
    Lapin
    Clonalité
    • 33
    • 10
    Polyclonal
    Conjugué
    • 26
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Cet anticorp CASP5 est non-conjugé
    Application
    • 25
    • 15
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Specificité
    Caspase-5 antibody was raised against a 14 amino acid peptide from the center of human Caspase-5.
    Purification
    Affinity chromatography purified via peptide column
    Immunogène
    Human Casp-5 / (ICH-3 / ICE rel III (Intermediate Domain) Peptide
    Isotype
    IgG
    Top Product
    Discover our top product CASP5 Anticorps primaire
  • Indications d'application
    ELISA. Western Blot: Casp-5 antibody can be used for the detection of caspase-5 at 0.5 - 1 μg/mLDepending on cell lines or tissues used, other cleavage products may be observed. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C.
  • Antigène
    CASP5 (Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5))
    Autre désignation
    Caspase-5 (CASP5 Produits)
    Synonymes
    anticorps ICE(rel)III, anticorps ICEREL-III, anticorps ICH-3, anticorps CASP5, anticorps caspase 5, anticorps caspase-5, anticorps CASP5, anticorps LOC100437308
    Sujet
    Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens (reviewed in 1). Members of this subfamily include caspase-1, -4, -5, and -12. Activation of these caspases results in the cleavage and activation of proinflammatory cytokines such as IL-1beta and IL-18 (2,3). Caspase-5 can interact with caspase-1, both are constituents of the NALP1 inflammasome, a complex that can trigger the cleavage of pro-IL-1beta (4). Expression of caspase-5 can be regulated by lipopolysaccharide (LPS) and IFN-gamma (5).Synonyms: CASP-5, CASP5, ICE(rel)-III, ICH-3 protease, ICH3, TY protease
    ID gène
    838
    UniProt
    P51878
    Pathways
    Inflammasome
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