CBL anticorps (C-Term)
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- Antigène Voir toutes CBL Anticorps
- CBL (Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL))
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CBL est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
- Specificité
- This antibody reacts to CBL.
- Purification
- Affinity chromatography purified via peptide column
- Immunogène
- Cbl antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human cbl.
- Isotype
- IgG
- Top Product
- Discover our top product CBL Anticorps primaire
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- Indications d'application
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ELISA. Western Blot: Cbl antibody can be used for detection of cbl at 0.5 - 1 μg/mL. Immunofluorescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Buffer
- PBS containing 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C.
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- Antigène
- CBL (Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL))
- Autre désignation
- CBL / RNF55 (CBL Produits)
- Synonymes
- anticorps 4732447J05Rik, anticorps Cbl-2, anticorps c-Cbl, anticorps cbl, anticorps C-CBL, anticorps CBL2, anticorps FRA11B, anticorps NSLL, anticorps RNF55, anticorps c-cbl-like, anticorps RGD1561386, anticorps Casitas B-lineage lymphoma, anticorps Cbl proto-oncogene, anticorps Cbl, anticorps CBL
- Sujet
- The mammalian cbl family of ubiquitin ligases consists of three homologs known as cbl (also known as c-Cbl), Cbl-B, and Cbl-3 which share highly conserved a tyrosine-kinase-binding domain, linker and RING finger domain in their amino-terminal halves. Similar to other E3 ubiquitin ligases, Cbl catalyzes the transfer of ubiquitin from an E2 or Ubc (ubiquitin-conjugating) enzyme to the e-amino group of a lysine residue of the substrate protein. Cbl acts to negatively regulate many types of cell-surface receptors, including the Syk protein tyrosine kinase family. Cbl is thought to be involved in T- and B-cell signaling, in addition to thymus development. Of the three known homologs in the cbl family, cbl antibody reacts specifically with cbl. Multiple isoforms of cbl have been reported.Synonyms: CBL2, Casitas B-lineage lymphoma proto-oncogene, E3 ubiquitin-protein ligase CBL, Proto-oncogene c-CBL, RING finger protein 55, Signal transduction protein CBL, c-CBL
- ID gène
- 867
- UniProt
- P22681
- Pathways
- TCR Signaling, Interferon-gamma Pathway, EGFR Signaling Pathway, EGFR Downregulation, VEGFR1 Specific Signals
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