Acetyl-CoA Carboxylase beta anticorps (pSer220) (AbBy Fluor® 680)

N° du produit ABIN4995955

L’anticorps Lapin Polyclonal anti-Acetyl-CoA Carboxylase beta a été validé pour IF (cc) et IF (p). Il convient pour détecter Acetyl-CoA Carboxylase beta dans des échantillons de Humain.

Aperçu rapide pour Acetyl-CoA Carboxylase beta anticorps (pSer220) (AbBy Fluor® 680) (ABIN4995955)

Antigène: Acetyl-CoA Carboxylase beta (ACACB)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Acetyl-CoA Carboxylase beta est conjugé à/à la AbBy Fluor® 680

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-Acetyl-CoA Carboxylase beta anticorps (AbBy Fluor® 680)

Épitope: pSer220

Homologie: Human

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human Acetyl Coenzyme A Carboxylase beta around the phosphorylation site of Ser220

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur Acetyl-CoA Carboxylase beta

Antigène: Acetyl-CoA Carboxylase beta (ACACB)

Autre désignation: Acetyl Coenzyme A Carboxylase beta

Sujet:

Synonyms: Acetyl Coenzyme A Carboxylase beta phospho S220, Acetyl Coenzyme A Carboxylase beta phospho Ser2210 p-Acetyl Coenzyme A Carboxylase beta phospho S220, ACACB_HUMAN

Background: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

UniProt: O00763

Pathways: AMPK Signaling, Ribonucleoside Biosynthetic Process