CDIP1 anticorps (Center)

N° du produit ABIN499607

L’anticorps anti-CDIP1 Polyclonal Lapin est utilisé pour la détection de CDIP1 dans des échantillons de Humain et Souris. Il a été validé pour WB, IF, IHC (p) et EIA.

Aperçu rapide pour CDIP1 anticorps (Center) (ABIN499607)

Antigène: CDIP1 (LITAF-Like Protein (CDIP1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDIP1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-CDIP1 anticorps

Épitope: Center

Specificité: This antibody reacts to CDIP.

Purification: Affinity chromatography purified via peptide column

Immunogène: 19 amino acid peptide near the center of Human CDIP

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: CDIP antibody can be used for detection of CDIP at 0.25 - 0.5 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur CDIP1

Antigène: CDIP1 (LITAF-Like Protein (CDIP1))

Autre désignation: LITAF-Like Protein

Sujet: The p53 tumor-suppressor gene integrates numerous signals that control cell life and death, loss of its functions contributes to the development of most cancers. CDIP is a novel pro-apoptotic target gene whose inhibition abrogates p53-mediated apoptotic responses. Overexpression of CDIP induced apoptosis in transfected cells while siRNA suppression of caspase-8 mRNA blocked this CDIP-induced apoptosis, indicating that the CDIP-dependent apoptosis pathway proceeds through extrinsic cell death pathway. CDIP may thus represent a novel target for drug design to maximize p53 response and sensitize tumor cells to cancer therapy. Multiple isoforms of CDIP are known to exist.Synonyms: C16orf5, CDIP, Cell death-inducing protein, Transmembrane protein I1

ID gène: 29965

NCBI Accession: NP_037531

UniProt: Q9H305