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CDIP1 anticorps (AA 70-120)

CDIP1 Reactivité: Humain, Souris WB, ELISA, IF, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6991072
  • Antigène Voir toutes CDIP1 Anticorps
    CDIP1 (LITAF-Like Protein (CDIP1))
    Épitope
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 70-120
    Reactivité
    • 6
    • 4
    • 1
    Humain, Souris
    Hôte
    • 5
    • 2
    Lapin
    Clonalité
    • 7
    Polyclonal
    Conjugué
    • 7
    Cet anticorp CDIP1 est non-conjugé
    Application
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    CDIP Antibody is affinity chromatography purified via peptide column.
    Immunogène
    CDIP antibody was raised against a 19 amino acid synthetic peptide near the center of human CDIP. The immunogen is located within amino acids 70 - 120 of CDIP.
    Isotype
    IgG
    Top Product
    Discover our top product CDIP1 Anticorps primaire
  • Indications d'application
    CDIP antibody can be used for detection of CDIP by Western blot at 0.25 - 0.5 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    CDIP Antibody is supplied in PBS containing 0.02 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,4 °C
    Stockage commentaire
    CDIP antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Antigène
    CDIP1 (LITAF-Like Protein (CDIP1))
    Autre désignation
    CDIP (CDIP1 Produits)
    Synonymes
    anticorps RGD1310686, anticorps MGC165666, anticorps MGC97537, anticorps 2700048O17Rik, anticorps 5730403B10Rik, anticorps AU018521, anticorps AW742692, anticorps CDIP, anticorps C16orf5, anticorps I1, anticorps LITAFL, anticorps MGC52765, anticorps MGC127651, anticorps cell death-inducing p53 target 1, anticorps LITAF-like protein, anticorps cell death inducing Trp53 target 1, anticorps cell death inducing p53 target 1, anticorps cell death-inducing p53 target 1 L homeolog, anticorps Cdip1, anticorps cdip1, anticorps Bm1_00175, anticorps LOC100168843, anticorps CDIP1, anticorps cdip1.L
    Sujet
    CDIP Antibody: The p53 tumor-suppressor gene integrates numerous signals that control cell life and death, loss of its functions contributes to the development of most cancers. CDIP is a novel pro-apoptotic target gene whose inhibition abrogates p53-mediated apoptotic responses. Overexpression of CDIP induced apoptosis in transfected cells while siRNA suppression of caspase-8 mRNA blocked this CDIP-induced apoptosis, indicating that the CDIP-dependent apoptosis pathway proceeds through extrinsic cell death pathway. CDIP may thus represent a novel target for drug design to maximize p53 response and sensitize tumor cells to cancer therapy. Multiple isoforms of CDIP are known to exist.
    ID gène
    29965
    NCBI Accession
    NP_037531
    UniProt
    Q9H305
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