CDX2 anticorps (C-Term)

N° du produit ABIN499613

L’anticorps anti-CDX2 Polyclonal Lapin est utilisé pour la détection de CDX2 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB et EIA.

Aperçu rapide pour CDX2 anticorps (C-Term) (ABIN499613)

Antigène: CDX2 (Caudal Type Homeobox 2 (CDX2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDX2 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-CDX2 anticorps

Épitope: C-Term

Purification: Affinity chromatography purified via peptide column

Immunogène: CDX2 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human CDX2.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: CDX2 antibody can be used for detection of CDX2 at 1 - 2 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at -20 °C.

Détails sur CDX2

Antigène: CDX2 (Caudal Type Homeobox 2 (CDX2))

Autre désignation: Cdx2

Sujet: CDX2 is a member of the caudal homeobox family of transcription factors that also includes the proteins CDX1 and CDX4. CDX2 is strongly expressed in the trophectoderm in the blastocyst with expression maintained within the proliferating extra-embryonic ectoderm during development. It is required for the repression of the transcription of the POU5F1/Oct4 and NANOG genes in the outer cells of the blastocyst and is thus essential for the segregation of the inner cell mass and trophectoderm at the blastocyst stage. Aberrant expression of CDX2 is associated with numerous types of carcinomas, including intestinal metaplasia, gastric carcinoma, and acute myeloid leukemia due to deregulated HOX gene expression.Synonyms: CDX-3, CDX3, Caudal-type homeobox protein 2, Homeobox protein CDX-2

ID gène: 1045

UniProt: Q99626

Pathways: Peptide Hormone Metabolism, Stem Cell Maintenance