CENPO anticorps (Center)

N° du produit ABIN499615

Cet anticorps Lapin Polyclonal détecte spécifiquement CENPO dans WB et EIA. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour CENPO anticorps (Center) (ABIN499615)

Antigène: CENPO (Centromere Protein O (CENPO))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CENPO est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-CENPO anticorps

Épitope: Center

Purification: Affinity chromatography purified via peptide column

Immunogène: CENPO antibody was raised against a 16 amino acid peptide from near the center of human CENPO.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: CENPO antibody can be used for detection of CENPO at 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at -20 °C.

Détails sur CENPO

Antigène: CENPO (Centromere Protein O (CENPO))

Autre désignation: CENP-O

Sujet: Accurate chromosome segregation during mitosis requires a kinetochore to assemble correctly at the centromere of each chromatid and form a dynamic interface with the microtubules of the mitotic spindle. The kinetochore assembly includes the multisubunit CENP-H/I complex which can be divided into three functional classes based on phenotype analysis. One of these classes is referred to as the CENP-O class of proteins of which CENPO is the exemplar. These proteins form a stable complex with each other and are required for proper kinetochore function and for recovery from mitotic spindle damage. CENPO has also been shown to be an auto-antigen in a small population of anti-centromere antibodies- (ACA-) positive patients with sclerodoma.Synonyms: CENPO, Centromere protein O, ICEN36, Interphase centromere complex protein 36

ID gène: 79172

NCBI Accession: NP_077298

UniProt: Q9BU64