Adrenomedullin anticorps (AA 1-100) (AbBy Fluor® 680)

N° du produit ABIN4996167

Cet anticorps Lapin Polyclonal détecte spécifiquement Adrenomedullin dans IF (cc) et IF (p). Il présente une réactivité envers Rat.

Aperçu rapide pour Adrenomedullin anticorps (AA 1-100) (AbBy Fluor® 680) (ABIN4996167)

Antigène: Adrenomedullin (ADM)

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Adrenomedullin est conjugé à/à la AbBy Fluor® 680

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-Adrenomedullin anticorps (AbBy Fluor® 680)

Épitope: AA 1-100

Réactivité croisée: Rat

Homologie: Human,Mouse,Dog,Cow,Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human ADM

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur Adrenomedullin

Antigène: Adrenomedullin (ADM)

Autre désignation: Adrenomedullin

Classe de substances: Hormone

Sujet:

Synonyms: Adrenomedullin, ADM, AM, Contains, RecName, Proadrenomedullin N-20 terminal peptide, ProAM N-terminal 20 peptide, ProAM-N20, PAMP, ProAM-N20, ADML_HUMAN.

Background: Adrenomedullin (ADM), a vasodilator produced by most contractile cells, is characterized by persistent hypotensive activity. ADM is involved in the regulation of fluid and electrolyte homeostasis and in the maintenance of cardiovascular functioning. In hypertensive patients, the level of ADM in plasma is up-regulated. Natriuresis is a common systemic manifestation of aneurysmal subarachnoid hemorrhage. ADM has strong natriuretic actions. ADM-induced natriuresis is caused by an increase in glomerular filtration rate and a decrease in distal tubular sodium reabsorption. ADM is present both in the periphery and brain, and can exert central effects such as decreasing food ingestion.

ID gène: 133

Pathways: Hormone Transport, Hormone Activity, C21-Steroid Hormone Metabolic Process, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Tube Formation