C1QTNF2 anticorps

N° du produit ABIN499665

Cet anticorps anti-C1QTNF2 est un anticorps Lapin Polyclonal détectant C1QTNF2 dans WB, IF et EIA. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour C1QTNF2 anticorps (ABIN499665)

Antigène: C1QTNF2 (C1q and Tumor Necrosis Factor Related Protein 2 (C1QTNF2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C1QTNF2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Détail du produit anti-C1QTNF2 anticorps

Specificité: CTRP2 antibody was raised against recombinant human CTRP2.

Purification: Affinity Purified

Immunogène: Recombinant mouse CTRP2

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: CTRP2 antibody can be used for the detection of CTRP2 at 1 μg/mL. Caco-2cell lysate can be used as positive control. These proteins are often highly modifiedpost-translationally and migrate in SDS-PAGE at positions other than their predicted size. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur C1QTNF2

Antigène: C1QTNF2 (C1q and Tumor Necrosis Factor Related Protein 2 (C1QTNF2))

Autre désignation: C1QTNF2

Sujet: Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines (reviewed in 1). One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-related proteins (CTRPs) 1-7 (2). Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are are expressed in a wide variety of tissues (3). These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene (4). Of the CTRPs, CTRP2 is most similar structurally and functionally to adiponectin. Recombinant CTRP2 rapidly activated AMPK and MAPK in cultured C2C12 cells, leading to increased glycogen accumulation and fatty acid oxidation (3).Synonyms: CTRP2, Complement C1q tumor necrosis factor-related protein 2

ID gène: 114898

NCBI Accession: NP_114114

UniProt: Q9BXJ5