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C1QTNF2 anticorps

C1QTNF2 Reactivité: Humain, Souris, Rat WB, IF, EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN499665
  • Antigène Tous les produits C1QTNF2
    C1QTNF2 (C1q and Tumor Necrosis Factor Related Protein 2 (C1QTNF2))
    Reactivité
    • 39
    • 8
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 34
    • 4
    • 1
    Lapin
    Clonalité
    • 37
    • 2
    Polyclonal
    Conjugué
    • 22
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp C1QTNF2 est non-conjugé
    Application
    • 32
    • 21
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Specificité
    CTRP2 antibody was raised against recombinant human CTRP2.
    Purification
    Affinity Purified
    Immunogène
    Recombinant mouse CTRP2
    Isotype
    IgG
  • Indications d'application
    ELISA. Western Blot: CTRP2 antibody can be used for the detection of CTRP2 at 1 μg/mL. Caco-2cell lysate can be used as positive control. These proteins are often highly modifiedpost-translationally and migrate in SDS-PAGE at positions other than their predicted size. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C.
  • Antigène
    C1QTNF2 (C1q and Tumor Necrosis Factor Related Protein 2 (C1QTNF2))
    Autre désignation
    C1QTNF2 (C1QTNF2 Produits)
    Synonymes
    anticorps C1QTNF2, anticorps fe50b04, anticorps wu:fe50b04, anticorps CTRP2, anticorps zacrp2, anticorps 1810033K05Rik, anticorps Ctrp2, anticorps RGD1561041, anticorps C1q and tumor necrosis factor related protein 2, anticorps C1q and TNF related 2, anticorps C1QTNF2, anticorps c1qtnf2, anticorps C1qtnf2
    Sujet
    Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines (reviewed in 1). One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-related proteins (CTRPs) 1-7 (2). Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are are expressed in a wide variety of tissues (3). These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene (4). Of the CTRPs, CTRP2 is most similar structurally and functionally to adiponectin. Recombinant CTRP2 rapidly activated AMPK and MAPK in cultured C2C12 cells, leading to increased glycogen accumulation and fatty acid oxidation (3).Synonyms: CTRP2, Complement C1q tumor necrosis factor-related protein 2
    ID gène
    114898
    NCBI Accession
    NP_114114
    UniProt
    Q9BXJ5
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