DDX3X anticorps (Intermediate Domain)

N° du produit ABIN499730

L’anticorps Lapin Polyclonal anti-DDX3X a été validé pour WB, IF et EIA. Il convient pour détecter DDX3X dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour DDX3X anticorps (Intermediate Domain) (ABIN499730)

Antigène: DDX3X (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3, X-Linked (DDX3X))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DDX3X est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Détail du produit anti-DDX3X anticorps

Épitope: Intermediate Domain

Purification: Affinity chromatography purified via peptide column

Immunogène: Human DDX3 (Intermediate Domain) Peptide

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western BLot: 1 - 2 μg/mL. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur DDX3X

Antigène: DDX3X (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3, X-Linked (DDX3X))

Autre désignation: DDX3X

Sujet: DDX3 contains all of the motifs of the DEAD-box family of RNA helicases, including the Asp-Glu-Ala-Asp sequence that gives the protein family its name and distinguishes it from other RNA helicases (1,2). DDX3 is localized to the X chromosome and has a highly conserved functional homolog (DBY) on the Y chromosome (3). DDX3 is thought to be involved in RNA splicing, RNA transport, and translation initiation (4). It has also been shown to be involved in cell growth control and is deregulated in hepatitis virus-associated hepatocellular carcinoma (5). Recent experiments suppressing DDX3 expression blocked HIV-1 RNA export from the nucleus, suggesting that DDX3 functions as a shuttling protein that transports the HIV-1 protein Rev and its cofactor CRM1 from the nucleus to the cytoplasm (6).Synonyms: ATP-dependent RNA helicase DDX3X, DBX, DDX3, DEAD box X isoform, DEAD box protein 3 X-chromosomal, DEAD3, Embryonic RNA helicase, HLP2, Helicase-like protein 2

ID gène: 1654

UniProt: O00571

Pathways: Ribonucleoprotein Complex Subunit Organization, Positive Regulation of Endopeptidase Activity, Negative Regulation of intrinsic apoptotic Signaling, Ribosome Assembly