beta Catenin anticorps (pTyr333) (AbBy Fluor® 680)

N° du produit ABIN4997387

Cet anticorps anti-beta Catenin est un anticorps Lapin Polyclonal détectant beta Catenin dans WB, FACS, IF (cc) et IF (p). Adapté pour Humain, Souris et Rat.

Aperçu rapide pour beta Catenin anticorps (pTyr333) (AbBy Fluor® 680) (ABIN4997387)

Antigène: beta Catenin (CATNB) (Catenin, beta (CATNB))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp beta Catenin est conjugé à/à la AbBy Fluor® 680

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-beta Catenin anticorps (AbBy Fluor® 680)

Épitope: pTyr333

Réactivité croisée: Humain, Souris, Rat

Homologie: Cow,Sheep,Pig,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human beta Catenin around the phosphorylation site of Tyr333

Isotype: IgG

Information d'application

Indications d'application: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur beta Catenin

Antigène: beta Catenin (CATNB) (Catenin, beta (CATNB))

Autre désignation: beta Catenin

Sujet:

Synonyms: beta Catenin phospho Y333, beta Catenin phospho Tyr333, p-beta Catenin Y333, p-beta Catenin Tyr333, beta-catenin, beta catenin, CTNNB1, CHBCAT, CTNNB1, CTNNB, PRO2286, Cadherin associated protein, Catenin cadherin associated protein, beta 1, 88 kDa, Catenin beta 1, Catenin beta-1, CATNB, CTNB1_HUMAN, CTNNB, CTNNB1, DKFZp686D02253, FLJ25606, FLJ37923, b-catenin, OTTHUMP00000162082, OTTHUMP00000165222, OTTHUMP00000165223, OTTHUMP00000209288, OTTHUMP00000209289.

Background: The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Oct 2009].

ID gène: 1499

Pathways: Peptide Hormone Metabolism