Emerin anticorps (N-Term)
Aperçu rapide pour Emerin anticorps (N-Term) (ABIN499790)
Antigène
Voir toutes Emerin (EMD) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Specificité
- This antibody reacts to Emerin.
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Purification
- Affinity chromatography purified via peptide column
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Immunogène
- Emerin antibody was raised against a 19 amino acid peptide from near the amino terminus of human Emerin.
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Isotype
- IgG
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Indications d'application
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ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Buffer
- PBS containing 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C.
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- Emerin (EMD)
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Autre désignation
- Emerin
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Sujet
- Emerin is a serine-rich nuclear membrane protein and a member of the nuclear lamina-associated protein family that includes proteins such as LAP2 and MAN1. Each family member, including Emerin, has an ~40 amino acid LEM-domains that binds barrier-to-autointegration (BANF1), a conserved chromatin protein that also serves as a host cell component of retroviral integration complexes, including that of HIV. Emerin is anchored at the inner membrane of the nuclear envelope where it binds to nuclear intermediate filaments that are formed by lamin proteins. Dreifuss-Emery muscular dystrophy is an X-linked inherited degenerative myopathy resulting from mutation in the emerin gene.Synonyms: EDMD, EMD, STA
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ID gène
- 2010
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NCBI Accession
- NP_000108
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UniProt
- P50402
Antigène
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