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FAM59A anticorps (C-Term)

FAM59A Reactivité: Humain, Souris, Rat WB, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN499824
  • Antigène Voir toutes FAM59A Anticorps
    FAM59A (Family with Sequence Similarity 59, Member A (FAM59A))
    Épitope
    • 15
    • 5
    • 1
    • 1
    C-Term
    Reactivité
    Humain, Souris, Rat
    Hôte
    • 21
    Lapin
    Clonalité
    • 21
    Polyclonal
    Conjugué
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp FAM59A est non-conjugé
    Application
    • 16
    • 13
    • 13
    • 8
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Purification
    Affinity chromatography purified via peptide column
    Immunogène
    FAM59A antibody was raised against a 19 amino acid peptide from near the carboxy terminus of human FAM59A.
    Isotype
    IgG
    Top Product
    Discover our top product FAM59A Anticorps primaire
  • Indications d'application
    ELISA. Western Blot: 1 - 2 μg/mL. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS containing 0.02 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    -20 °C
    Stockage commentaire
    Store the antibody (in aliquots) at -20 °C.
  • Antigène
    FAM59A (Family with Sequence Similarity 59, Member A (FAM59A))
    Autre désignation
    FAM59A (FAM59A Produits)
    Synonymes
    anticorps C18orf11, anticorps FAM59A, anticorps Gm944, anticorps C86169, anticorps Fam59a, anticorps mKIAA4238, anticorps fam59a, anticorps zgc:55634, anticorps GRB2 associated regulator of MAPK1 subtype 1, anticorps GRB2 associated, regulator of MAPK1, anticorps GAREM1, anticorps Garem1, anticorps garem
    Sujet
    FAM59A, also known as GAREM, was initially identified through a mass spectroscoptic method that measures different phosphotyrosine states of proteins in response to different cell stimuli. FAM59A is a downstream molecule in the EGF signaling pathway that is tyrosine-phosphorylated, and this phosphorylation is needed for the binding of Grb2, an adaptor protein crucial to the transduction of growth signals from the plasma membrane to the nucleus. ERK activation in response to EGF stimulation is regulated by FAM59A in COS-7 and HeLa cells, and the overexpression of FAM59A stimulated cell proliferation and colony formation in soft agar, suggesting that FAM59A might be a critical protein with roles in ligand-mediated signaling pathway of the EGF receptor and the tumorigenesis of cells.Synonyms: C18orf11
    ID gène
    64762
    UniProt
    Q9H706
    Pathways
    EGFR Signaling Pathway
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