FEZ1 anticorps (C-Term)

N° du produit ABIN499830

Détail du produit anti-FEZ1 anticorps

Antigène: FEZ1 (Fasciculation and Elongation Protein zeta 1 (Zygin I) (FEZ1))

Épitope: C-Term

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FEZ1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to FEZ1.

Purification: Affinity chromatography purified via peptide column

Immunogène: FEZ1 antibody was raised against a 19 amino acid peptide from near the carboxy terminus of human FEZ1.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur FEZ1

Antigène: FEZ1 (Fasciculation and Elongation Protein zeta 1 (Zygin I) (FEZ1))

Autre désignation: Zygin-1 (FEZ1 Produits)

Synonymes: anticorps UNC-76, anticorps UNC76, anticorps wu:fj14c12, anticorps zgc:73258, anticorps fez1, anticorps xfez1, anticorps fasciculation and elongation protein zeta 1, anticorps fasciculation and elongation protein zeta 1 (zygin I), anticorps fasciculation and elongation protein zeta 1 L homeolog, anticorps FEZ1, anticorps Fez1, anticorps fez1, anticorps fez1.L

Sujet: Similar to its C. elegans homolog UNC-76, mammalian FEZ1, an abundant membrane protein and protein kinase C (PKC)-Z substrate, is involved in axonal guidance. Following phosphorylation by PKC-Z, FEZ1 translocates from the plasma membrane to the cytoplasm. FEZ1 is then able to interact with a number of proteins involved in axonal outgrowth and cellular transport such as DISC1, a candidate gene for schizophrenia, as well as kinesin-1, a microtubule-based motor protein. FEZ1 also interacts with proteins involved in transcriptional regulation and chromatin remodeling, suggesting that FEZ1 may have nuclear regulatory functions in addition to those for neuronal development. At least two distinct isoforms of FEZ1 are known to exist. Despite its predicted molecular weight, FEZ1 will often run at higher molecular weight in SDS-PAGE.Synonyms: FEZ1, Fasciculation and elongation protein zeta-1, Zygin I

ID gène: 9638

UniProt: Q99689