Calcineurin B anticorps (pTyr106) (AbBy Fluor® 680)

N° du produit ABIN4998919

L’anticorps Lapin Polyclonal anti-Calcineurin B a été validé pour IF (cc) et IF (p). Il convient pour détecter Calcineurin B dans des échantillons de Poisson zèbre (Danio rerio).

Aperçu rapide pour Calcineurin B anticorps (pTyr106) (AbBy Fluor® 680) (ABIN4998919)

Antigène: Calcineurin B (CAN)

Reactivité: Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Calcineurin B est conjugé à/à la AbBy Fluor® 680

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-Calcineurin B anticorps (AbBy Fluor® 680)

Épitope: pTyr106

Réactivité croisée: Poisson zèbre (Danio rerio)

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit,Guinea Pig,Drosophila

Purification: Purified by Protein A.

Immunogène: KLH conjugated syntheticphosphopeptide derived from human Calcineurin B around the phosphorylation site of Tyr106

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur Calcineurin B

Antigène: Calcineurin B (CAN)

Autre désignation: Calcineurin B

Sujet:

Synonyms: Calcineurin B phospho Y106, Calcineurin B phospho Tyr106, p-Calcineurin B Tyr106, Calcineurin subunit B type 1, CALNB1, CANB1_HUMAN, Cna2, CNB, CNB1, OTTHUMP00000201960, OTTHUMP00000201961, Ppp3r1, PPP3R1 protein phosphatase 3 formerly 2B, regulatory subunit B, alpha isoform, alpha isoform calcineurin B, type I, calcineurin B, type I 19 kDa, protein phosphatase3 formerly2B, regulatory subunit B, alpha isoform antibody Protein phosphatase 2B regulatory subunit 1, Protein phosphatase 2B regulatory subunit B alpha, protein phosphatase 3 formerly 2B, regulatory subunit B, 19 kDa, alpha isoform calcineurin B, type I, Protein phosphatase 3 regulatory subunit B alpha, Protein phosphatase 3 regulatory subunit B alpha isoform 1.

Background: In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. In general, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit and a catalytic subunit. Four major families of protein phosphatase catalytic subunit have been identified, designated PP1, PP2A, PP2B and PP2C. An additional protein phosphatase catalytic subunit, PPX (also known as PP4), is a putative member of a novel PP family. The PP2B family comprises subfamily members PP2B-A alpha, PP2B-A Beta and PP2B-A Gamma. Two additional regulatory subunits been identified, designated PP2B-B1 and PP2B-B2.

ID gène: 5534

Pathways: Cellular Glucan Metabolic Process, VEGF Signaling