IER3 anticorps (Center)

N° du produit ABIN499960

Cet anticorps Lapin Polyclonal détecte spécifiquement IER3 dans WB, IHC (p) et EIA. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour IER3 anticorps (Center) (ABIN499960)

Antigène: IER3 (Immediate Early Response 3 (IER3))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IER3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-IER3 anticorps

Épitope: Center

Specificité: This antibody reacts to IEX1.

Purification: Affinity chromatography purified via peptide column

Immunogène: IEX1 antibody was raised against a 24 amino acid peptide near the center of human IEX1.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: 2 - 4 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur IER3

Antigène: IER3 (Immediate Early Response 3 (IER3))

Autre désignation: IER3 / IEX1

Sujet: IEX-1 is a stress inducible gene that is induced by ionizing radiation, ultraviolet radiation, and a variety of growth factors, i.e., FAS and TNF-a. IEX-1 is widely expressed in epithelial and endocrine tissues, as well as in vascular endothelium. It plays an important role in the regulation of cellular growth, cell death and oncogenesis. IEX-1 is precisely regulated by multiple transcription factors such as p53, NF-kappaB/rel, Sp1 and c-Myc, to ensure rapid and transient expression of IEX-1 in cells under a variety of stress conditions. IEX-1 is expressed as both a longer form (IEX1L) and a splice variant, designated IEX1S. It is localized to the nucleus and perinuclear region. Overexpression of IEX-1 facilitates apoptosis and cell cycle progression, whereas disruption of IEX-1 expression is associated with decreases in both apoptosis and cell cycle progression.Synonyms: DIF2, Differentiation-dependent gene 2 protein, GLY96, IEX-1, Immediate early protein GLY96, Immediate early response 3 protein, PACAP-responsive gene 1 protein, PRG1, Radiation-inducible immediate-early gene IEX-1

ID gène: 8870

UniProt: P46695

Pathways: Regulation of Carbohydrate Metabolic Process