FBXO43 anticorps (C-Term)

N° du produit ABIN499984

Cet anticorps Lapin Polyclonal détecte spécifiquement FBXO43 dans WB, IF et EIA. Il présente une réactivité envers Humain.

Aperçu rapide pour FBXO43 anticorps (C-Term) (ABIN499984)

Antigène: FBXO43 (F-Box Protein 43 (FBXO43))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FBXO43 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Détail du produit anti-FBXO43 anticorps

Épitope: C-Term

Specificité: IL-1RAcP antibody was raised against a peptide corresponding to amino acids near the carboxy terminus of IL-1RAcP, which differs from the sequence of mouse origin by three amino acids. It has no cross activity to other member in the IL-1 receptor family.

Purification: Affinity chromatography purified via peptide column

Immunogène: Human IL-1RAcP (C-Terminus) Peptide

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: 1/500 to 1/1000. An approximately 66 kDa band can be detected.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Détails sur FBXO43

Antigène: FBXO43 (F-Box Protein 43 (FBXO43))

Autre désignation: FBXO43

Sujet: The pro-inflammatory cytokine IL-1 induced cellular response requires two subunits of its receptor, IL-1 receptor I(IL-1RI) and IL-1 receptor accessory protein (IL-1RAcP) (1).IL-1 RAcP forms a complex with IL-1RI in response to IL-1 treatment. The IL-1 receptor-associated kinase (IRAK), which mediates activation of NF-kappaB inducing kinae (NIK) and of NF-kappaB, recruites to the IL-1R complex through IL-1 RAcP(2). IL-1 activation of stress-activated protein kinase and of acid sphingomyelinase also requires IL-1RAcP(3,4). Like IL-1RI, IL-1RAcP subunit is essential for IL-1 mediated cellular response. IL-1RAcP is expressed in many tissues.Synonyms: EMI2, Endogenous meiotic inhibitor 2, F-box only protein 43, FBP5B

ID gène: 100101275

UniProt: Q8AXF4