IL-34 anticorps (N-Term)

N° du produit ABIN500016

Cet anticorps anti-IL-34 Polyclonal Lapin (ABIN500016) détecte spécifiquement IL-34 dans WB et EIA. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour IL-34 anticorps (N-Term) (ABIN500016)

Antigène: IL-34 (IL34) (Interleukin 34 (IL34))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL-34 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-IL-34 anticorps

Épitope: N-Term

Specificité: This antibody reacts to IL-34.

Réactivité croisée (Details): Species reactivity (tested):Human brain tissue.

Purification: Affinity chromatography purified via peptide column

Immunogène: IL-34 antibody was raised against a 16 amino acid peptide from near the amino terminus of human IL-34.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: 0.25 - 0.5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Détails sur IL-34

Antigène: IL-34 (IL34) (Interleukin 34 (IL34))

Autre désignation: Interleukin-34 / IL34

Sujet: Interleukin-34 (IL-34) was identified through a functional screening of a library of secreted proteins after transfection of an embryonic kidney cell line with recombinant cDNAs. Flow cytometry and monocyte viability assays demonstrated increased survival and/or proliferation of monocytes induced by IL-34 and specific binding of IL-34 to CD14+ monocytes. IL-34 is a second ligand to the colony stimulating factor (CSF)-1 receptor in addition to CSF1. Like CSF1, IL-34 stimulates phosphorylation of ERK1 and ERK2 in human monocytes and induces differentiation of bone marrow cells into macrophages. Despite its predicted molecular weight, IL-34 will often run at higher molecular weight in SDS-PAGE.Synonyms: C16orf77, IL-34

ID gène: 146433

UniProt: Q6ZMJ4

Pathways: Signalisation RTK