NKIRAS1 anticorps (Center)

N° du produit ABIN500110

Cet anticorps Lapin Polyclonal détecte spécifiquement NKIRAS1 dans WB, IHC (p) et EIA. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour NKIRAS1 anticorps (Center) (ABIN500110)

Antigène: NKIRAS1 (NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NKIRAS1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-NKIRAS1 anticorps

Épitope: Center

Specificité: This antibody detects both kappaB-ras1 and kappaB-ras2.

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Purification: Peptide afinity chromatography

Immunogène: KappaB ras antibody was raised against a 18 amino acid peptide from near the center of human KappaB ras 1.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot: 2 - 4 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur NKIRAS1

Antigène: NKIRAS1 (NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1))

Autre désignation: NKIRAS1

Sujet: KappaB ras-1 (kappaB-ras-1) and kappaB-ras-2 are two small proteins that similar to Ras-like small GTPases that associate with IkappaB (IkappaB), an inhibitor of the transcription factor NF-kappaB. IkappaB exists in two homologous forms, IkappaB-alpha and IkappaB-beta, although IkappaB-beta contains a unique 47-amino acid region within its ankyrin domain. While inactive IkappaB-alpha-NF-kappaB complexes can shuttle in and out of the nucleus, IkappaB-beta-NF-kappaB complexes are retained exclusively in the cytoplasm. It is suggested that kappaB-ras proteins preferentially bind to the IkappaB-beta form through this unique insert within the ankyrin region, thus modulating the cellular location of IkappaB-beta and regulating the rate of degradation of IkappaB-beta.Synonyms: KBRAS1, NF-kappa-B inhibitor-interacting Ras-like protein 1

ID gène: 28512

UniProt: Q9NYS0