SCARB2 anticorps (C-Term)

N° du produit ABIN500174

L’anticorps Lapin Polyclonal anti-SCARB2 a été validé pour WB, IHC (p) et EIA. Il convient pour détecter SCARB2 dans des échantillons de Humain et Souris.

Aperçu rapide pour SCARB2 anticorps (C-Term) (ABIN500174)

Antigène: SCARB2 (Scavenger Receptor Class B, Member 2 (SCARB2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SCARB2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-SCARB2 anticorps

Épitope: C-Term

Specificité: This antibody detects SCARB2 at C-term.

Réactivité croisée (Details): Species reactivity (tested):Human, mouse

Purification: Peptide affinity chromatography

Immunogène: LIMP2 antibody was raised against a 18 amino acid peptide from near the carboxy terminus of human LIMP2.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur SCARB2

Antigène: SCARB2 (Scavenger Receptor Class B, Member 2 (SCARB2))

Autre désignation: SCARB2

Sujet: The lysosomal integral membrane protein 2 (LIMP2) is a heavily glycosylated type III transmembrane protein, the majority of which exists in the lumen of the lysosome and a cytoplasmic domain of approximately 20 amino acids. A deficiency of LIMP2 in mice causes uretic pelvic junction obstruction, deafness, and peripheral neuropathy associated with impaired vesicular trafficking and distribution of apically expressed proteins. More recently, LIMP2 was shown to act as a receptor to bind b-glucocerebrosidase, the enzyme defective in Gaucher disease, a lysosomal storage disorder. LIMP2-deficient mice showed missorted as well as secreted b-glucocerebrosidase, suggesting that LIMP2 also functions as the mannose-6-phosphate-independent trafficking receptor. Despite its predicted molecular weight, LIMP2 runs at approximately 80 - 85 kDa in SDS-PAGE.Synonyms: 85 kDa lysosomal membrane sialoglycoprotein, CD36 antigen-like 2, CD36L2, LGP85, LIMP II, LIMP2, LIMPII, Lysosome membrane protein 2, SR-BII, SRB2, Scavenger receptor class B member 2

ID gène: 950

UniProt: Q14108