EED anticorps (AA 51-150) (AbBy Fluor® 750)

N° du produit ABIN5001747

Cet anticorps Lapin Polyclonal détecte spécifiquement EED dans WB, IF (cc) et IF (p). Il présente une réactivité envers Xenopus laevis, Killifish (Oryzias latipes) et Xenopus tropicalis.

Aperçu rapide pour EED anticorps (AA 51-150) (AbBy Fluor® 750) (ABIN5001747)

Antigène: EED (Embryonic Ectoderm Development (EED))

Reactivité: Xenopus laevis, Killifish (Oryzias latipes), Xenopus tropicalis

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EED est conjugé à/à la AbBy Fluor® 750

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-EED anticorps (AbBy Fluor® 750)

Épitope: AA 51-150

Réactivité croisée: Killifish (Oryzias latipes), Xenopus laevis, Xenopus tropicalis

Homologie: Human,Mouse,Rat,Cow,Sheep,Pig,Horse,Chicken,Rabbit,Zebrafish

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human EED

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur EED

Antigène: EED (Embryonic Ectoderm Development (EED))

Autre désignation: EED

Sujet:

Synonyms: eed, EED protein, EED_HUMAN, Embryonic ectoderm development, Embryonic ectoderm development isoform a, Embryonic ECTODERM development protein homolog, hEED, OTTHUMP00000235483, OTTHUMP00000235484, OTTHUMP00000235485, Polycomb protein eed, WAIT 1, WAIT-1, WAIT1, WD protein associating with integrin cytoplasmic tails 1.

Background: The transcriptional repressing Polycomb-group (PcG) and transcriptional activating trithorax-group (trxG) genes of Drosophila are part of a cellular memory system responsible for the stable inheritance of gene activity. PcG proteins assemble into multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. EED (embryonic ectoderm development) is the human homolog of Eed, a murine PcG gene homologous to the Drosophila homeotic gene, extra sex combs. The human EED protein is 99. 5 % identical to the mouse EED protein and contains seven WD repeats, which are involved in protein-protein interactions. There are two human EED transcripts that contain a putative 407-nucleotide-long intron and give rise to two HEED protein isoforms, 535 and 494 amino acids in length. EED interacts in a highly specific manner, both in vitro and in vivo, with histone deacetylase (HDAC) proteins.

ID gène: 8726