MTCH2 anticorps (N-Term)
Aperçu rapide pour MTCH2 anticorps (N-Term) (ABIN500296)
Antigène
Voir toutes MTCH2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Specificité
- This antibody detects MTCH2.
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Réactivité croisée (Details)
- Species reactivity (tested):Human
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Purification
- Peptide affinity chromatography
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Immunogène
- MTCH2 antibody was raised against a 15 amino acid peptide near the amino terminus of human MTCH2.
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Isotype
- IgG
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Indications d'application
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ELISA. Western blot: 1 - 2 μg/mL. Immunohistochgemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Buffer
- PBS containing 0.02 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- MTCH2 (Mitochondrial Carrier 2 (MTCH2))
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Autre désignation
- MTCH2
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Sujet
- Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death. MTCH2 is a member of the mitochondrial carrier protein family that catalyze the exchange of substrates across the inner mitochondrial membrane and is targeted by Bid, a pro-apoptotic Bcl-2 family member, in response to apoptotic signals, suggesting that MTCH2 may play a key role in the mitochondrial apoptosis pathway.Synonyms: HSPC032, MIMP, Met-induced mitochondrial protein, Mitochondrial carrier homolog 2
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ID gène
- 56428
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UniProt
- Q791V5
Antigène
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