NANOS2 anticorps (N-Term)

N° du produit ABIN500322

Détail du produit anti-NANOS2 anticorps

Antigène: NANOS2 (Nanos Homolog 2 (NANOS2))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NANOS2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Specificité: This antibody detects NANOS2 at N-term. It will not cross-react with either Nanos 1 or Nanos3.

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Purification: Peptide affinity chromatography

Immunogène: Nanos2 antibody was raised against a 13 amino acid peptide near the amino terminus of the human Nanos2.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur NANOS2

Antigène: NANOS2 (Nanos Homolog 2 (NANOS2))

Autre désignation: NANOS2 (NANOS2 Produits)

Synonymes: anticorps NOS2, anticorps RGD1562436, anticorps nos2, anticorps nanos C2HC-type zinc finger 2, anticorps nanos homolog 2 (Drosophila), anticorps nanos 2, anticorps nanos2 protein, anticorps NANOS2, anticorps Nanos2, anticorps nanos2

Sujet: Nanos is a zinc-finger containing, RNA-binding protein that has been implicated in germ cell development in both invertebrates and vertebrates. In drosophila, Nanos represses apoptosis during development to ensure proper germ-line development. Unlike Nanos1 whose expression in mice is dispensable, the Nanos2 and Nanos3 proteins are required for germ cell development. Nanos2-null primordial germ cells (PGCs) die only in the male gonads and show no defects in females, while Nanos3-null PGCs are lost during the migration stage regardless of sex. Nanos2 and Nanos3 have distinct expression patterns during embryo development, suggesting that these two proteins do not have redundant functions. However, expression of Nanos2 can at least partially replace Nanos3 function in a Nanos3-null background. Nanos3 expression can not rescue Nanos2-null defects.Synonyms: NOS2, Nanos homolog 2

ID gène: 339345

UniProt: P60321

Pathways: Retinoic Acid Receptor Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Stem Cell Maintenance