NUP107 anticorps (C-Term)

N° du produit ABIN500395

Cet anticorps Lapin Polyclonal détecte spécifiquement NUP107 dans WB, IF et EIA. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour NUP107 anticorps (C-Term) (ABIN500395)

Antigène: NUP107 (Nucleoporin 107kDa (NUP107))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NUP107 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Détail du produit anti-NUP107 anticorps

Épitope: C-Term

Specificité: This antibody detects NUP107 at C-term.

Purification: Immunoaffinity chromatography

Immunogène: NUP107 antibody was raised against a 15 amino acid peptide from near the carboxy terminus of human NUP107.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot: 1 - 2 μg/mL. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: PBS containing 0.02 % sodium azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur NUP107

Antigène: NUP107 (Nucleoporin 107kDa (NUP107))

Autre désignation: NUP107

Sujet: The nuclear pore complex (NPC) is a protein assembly localized at the nuclear rim and mediates macromolecular transport between the nucleus and the cytoplasm. The mammalian nucleoporin (NUP)-107 is part of the hetero-oligomeric complex that also contains NUP160, NUP133, NUP96, and mammalian homolog of yeast sec13p. While the majority of the NUP107-160 nuclear pore sub-complex localizes to the nuclear pore, a small fraction is observed at kinetochores and pro-metaphase spindle poles in mitotic cells in association with proteins such as Mad1, Mad2, Bub3 and Cdc20. Immunodepletion of the NUP107-160 complex resulted in defective spindle assembly indicating that it has multiple functions. NUP107 has recently been identified as an HIV dependency factor (HDF), suggesting that NUP107 may be an important drug target in HIV treatment. Multiple isoforms of NUP107 are known to exist.Synonyms: NUP84, Nuclear pore complex protein Nup107, Nucleoporin Nup107

ID gène: 57122

UniProt: P57740

Pathways: Protein targeting to Nucleus