Stathmin 1 anticorps (C-Term)

N° du produit ABIN500415

Cet anticorps anti-Stathmin 1 est un anticorps Lapin Polyclonal détectant Stathmin 1 dans WB, IHC (p) et EIA. Adapté pour Humain et Souris.

Aperçu rapide pour Stathmin 1 anticorps (C-Term) (ABIN500415)

Antigène: Stathmin 1 (STMN1)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Stathmin 1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-Stathmin 1 anticorps

Épitope: C-Term

Specificité: This antibody detects Stathmin / STMN1 at C-term.

Réactivité croisée (Details): Species reactivity (tested):Human, mouse

Purification: Peptide affinity chromatography

Immunogène: Op18 antibody was raised against a 20 amino acid peptide from near the carboxy terminus of human op18.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur Stathmin 1

Antigène: Stathmin 1 (STMN1)

Autre désignation: Stathmin / STMN1

Sujet: Op18 belongs to the stathmin family of genes and encodes a ubiquitous cytosolic phosphoprotein that may function as an intracellular relay integrating several signaling pathways such as those involved in cell proliferation and differentiation. Op18 has also been shown to be involved in the regulation of the microtubule filament system by destabilizing microtubules, thereby preventing assembly and promoting the disassembly of microtubules. More recently, op18 has been implicated as a potential target of the ASK1-p38 MAP kinase cascade, suggesting that the ASK1-p38 cascade may regulate microtubule dynamics through op18. Op18 is highly expressed in a wide variety of human malignancies, including leukemia, prostate cancer, ovarian carcinoma, and breast carcinoma, suggesting that op18 may be an ideal target for anti-cancer therapeutics.Synonyms: LAP18, Leukemia-associated phosphoprotein p18, Metablastin, OP18, Oncoprotein 18, Op18, Phosphoprotein p19, Prosolin, Protein Pr22, pp17, pp19

ID gène: 3925

UniProt: P16949

Pathways: Signalisation MAPK, Dynamique des Microtubules