SPAG9 anticorps (AA 101-188) (AbBy Fluor® 680)

N° du produit ABIN5005667

Cet anticorps anti-SPAG9 est un anticorps Lapin Polyclonal détectant SPAG9 dans IF (cc) et IF (p). Adapté pour Souris.

Aperçu rapide pour SPAG9 anticorps (AA 101-188) (AbBy Fluor® 680) (ABIN5005667)

Antigène: SPAG9 (Sperm Associated Antigen 9 (SPAG9))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SPAG9 est conjugé à/à la AbBy Fluor® 680

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-SPAG9 anticorps (AbBy Fluor® 680)

Épitope: AA 101-188

Réactivité croisée: Souris

Homologie: Human,Rat,Dog,Sheep,Horse,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human JLP/JIP-4

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur SPAG9

Antigène: SPAG9 (Sperm Associated Antigen 9 (SPAG9))

Autre désignation: JLP/JIP-4

Sujet:

Synonyms: C jun amino terminal kinase interacting protein 4, c Jun NH2 terminal kinase associated leucine zipper protein, FLJ13450, FLJ14006, FLJ34602, HLC 4, HLC 4 protein, HLC 6, HLC4, HLC4 protein, HLC6, HSS, Human lung cancer protein 6, Human lung cancer protein 6, JIP 4, JIP 4, JIP4, JNK associated leucine zipper protein 1, JNK associated leucine zipper protein, JNK interacting protein 4, JNK interacting protein 4, JNK interacting protein, JNK/SAPK associated protein, KIAA0516, Lung cancer oncogene 4, MAPK8IP4, Max binding protein, MGC117291, MGC14967, MGC74461, Mitogen activated protein kinase 8 interacting protein 4, Mitogen activated protein kinase 8 interacting protein 4, PHET, PIG 6, PIG6, proliferation inducing gene 6, Protein highly expressed in testis, SPAG 9, SPAG9, Sperm associated antigen 9, Sperm specic protein, Sperm surface protein, Sunday driver drosophila homolog, Sunday driver 1, SYD1, JIP4_HUMAN.

Background: JIP-4 is a 1,321 amino acid protein encoded by the human gene SPAG9. It contains a large N-terminal extracellular domain, a short transmembrane helical domain, and a cytoplasmic domain. There are 6 N-glycosylation sites, several phosphorylation sites for cAMP/cGMP-dependent protein kinase, protein kinase C, and casein kinase II, and 10 putative myristoylation sites. There is also a leucine zipper motif, with 6 leucine repeats, that may aid in dimerization since there is no upstream basic domain characteristic of DNA binding proteins. The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. JIP-4 is a cytoplasmic, perinuclear protein that has eight known isoforms whose expression varies by tissue and disease state.

ID gène: 9043

UniProt: O60271

Pathways: Regulation of Muscle Cell Differentiation