RGS21 anticorps (Center)

N° du produit ABIN500587

Cet anticorps Lapin Polyclonal détecte spécifiquement RGS21 dans WB, IHC (p) et EIA. Il présente une réactivité envers Humain.

Aperçu rapide pour RGS21 anticorps (Center) (ABIN500587)

Antigène: RGS21 (Regulator of G-Protein Signaling 21 (RGS21))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RGS21 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-RGS21 anticorps

Épitope: Center

Specificité: This antibody detects RGS21.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Peptide Affinity Chromatography

Immunogène: RGS21 antibody was raised against a 16 amino acid peptide near the center of Human RGS21.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot: 1-2 μg/mL (HepG2 cells as recommended Positive Control). Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur RGS21

Antigène: RGS21 (Regulator of G-Protein Signaling 21 (RGS21))

Autre désignation: RGS21

Sujet: Regulator of G-protein signaling (RGS) proteins contain an 120 amino acid conserved domain, termed the RGS domain, that acts as a GTPase-activating protein that acts to reduce the signal transmitted by the receptor-activated G-alpha subunit. RGS21 is a recently identified member of this family that has been reported to be selectively expressed in subpopulations of taste bud cells and co-expressed with bitter and sweet transduction components such as alpha-gusticin, phospholipase Cbeta2, T1R2/T1R3 sweet taste receptors and T2R bitter taste receptors. Other reports indicate that RGS21 is more widely expressed. Binding assays demonstrate that RGS21 binds alpha-gusticin in a conformation-dependent manner and may do the same with T1R receptors, suggesting that RGS21 may play a role in sweet and bitter taste transduction processes.Synonyms: Regulator of G-protein signaling 21

ID gène: 431704

NCBI Accession: NP_001034241

UniProt: Q2M5E4

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling