KRT17 anticorps (Biotin)
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- Antigène Voir toutes KRT17 Anticorps
- KRT17 (Keratin 17 (KRT17))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp KRT17 est conjugé à/à la Biotin
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Application
- Western Blotting (WB)
- Réactivité croisée
- Humain
- Purification
- Purified by Protein G.
- Immunogène
- KLH conjugated synthetic peptide derived from human KRT17
- Clone
- 12B1
- Isotype
- IgG
- Top Product
- Discover our top product KRT17 Anticorps primaire
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- Indications d'application
- WB 1:300-5000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C for 12 months.
- Date de péremption
- 12 months
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- Antigène
- KRT17 (Keratin 17 (KRT17))
- Autre désignation
- KRT17 (KRT17 Produits)
- Synonymes
- anticorps K17, anticorps Krt1-17, anticorps PC, anticorps PC2, anticorps PCHC1, anticorps Ka17, anticorps KRT17, anticorps krt16, anticorps si:dkeyp-113d7.7, anticorps KRT14, anticorps keratin 17, anticorps keratin 17 L homeolog, anticorps keratin 17, type I, anticorps keratin, type I cytoskeletal 17, anticorps Krt17, anticorps KRT17, anticorps krt17, anticorps krt17.L, anticorps LOC100737113, anticorps LOC102177275
- Sujet
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Synonyms: Keratin, type I cytoskeletal 17, KRT17, 39.1, Cytokeratin-17, Keratin-17, K17
Background: Type I keratin involved in the formation and maintenance of various skin appendages, specifically in determining shape and orientation of hair (By similarity). Required for the correct growth of hair follicles, in particular for the persistence of the anagen (growth) state (By similarity). Modulates the function of TNF-alpha in the specific context of hair cycling. Regulates protein synthesis and epithelial cell growth through binding to the adapter protein SFN and by stimulating Akt/mTOR pathway (By similarity). Involved in tissue repair. May be a marker of basal cell differentiation in complex epithelia and therefore indicative of a certain type of epithelial "stem cells". Acts as a promoter of epithelial proliferation by acting a regulator of immune response in skin: promotes Th1/Th17-dominated immune environment contributing to the development of basaloid skin tumors (By similarity). May act as an autoantigen in the immunopathogenesis of psoriasis, with certain peptide regions being a major target for autoreactive T-cells and hence causing their proliferation.
- ID gène
- 3872
- UniProt
- Q04695
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