SIPA1L3 anticorps (N-Term)

N° du produit ABIN500720

Détail du produit anti-SIPA1L3 anticorps

Antigène: SIPA1L3 (Signal-Induced Proliferation-Associated 1 Like 3 (SIPA1L3))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SIPA1L3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Purification: Peptide affinity chromatography

Immunogène: SIPA1L3 antibody was raised against a 15 amino acid peptide from near the amino terminus of human SIPA1L3.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at -20 °C.

Détails sur SIPA1L3

Antigène: SIPA1L3 (Signal-Induced Proliferation-Associated 1 Like 3 (SIPA1L3))

Autre désignation: SIPA1L3 (SIPA1L3 Produits)

Synonymes: anticorps SPAL3, anticorps 2610511M17Rik, anticorps signal induced proliferation associated 1 like 3, anticorps signal-induced proliferation-associated 1 like 3, anticorps SIPA1L3, anticorps sipa1l3, anticorps Sipa1l3

Sujet: Signal-induced proliferation associated-like protein 2 (SIPA1L3) is a member of the SIPA1 family of RapGAPs. SIPA1L3 was cloned as a novel molecular component of tight junctions and adherens junctions, suggesting that may function to balance Rap1 by counteracting RapGEFs. Recent studies of SIPA indicate that its deregulation can cause myeloproliferative stem cell disorders in mice (3) and increased metastases in human cancers. Other studies suggest SIPA1L1 may play important roles in embryo development and control of cell proliferation. Based on the amount of homology between SIPA family members, it is possible that SIPA1L3 plays other roles development and cell proliferation.Synonyms: KIAA0545, SPA-1-like protein 3, SPAL3, Signal-induced proliferation-associated 1-like protein 3

ID gène: 23094

NCBI Accession: NP_055888

UniProt: O60292