SIPA1L3 anticorps (N-Term)

N° du produit ABIN6991229

Détail du produit anti-SIPA1L3 anticorps

Antigène: SIPA1L3 (Signal-Induced Proliferation-Associated 1 Like 3 (SIPA1L3))

Épitope: AA 80-130, N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SIPA1L3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Purification: SIPA1L3 Antibody is affinity chromatography purified via peptide column.

Immunogène: SIPA1L3 antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus of human SIPA1L3. The immunogen is located within amino acids 80 - 130 of SIPA1L3.

Isotype: IgG

Information d'application

Indications d'application: SIPA1L3 antibody can be used for detection of SIPA1L3 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: SIPA1L3 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: SIPA1L3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur SIPA1L3

Antigène: SIPA1L3 (Signal-Induced Proliferation-Associated 1 Like 3 (SIPA1L3))

Autre désignation: SIPA1L3 (SIPA1L3 Produits)

Synonymes: anticorps SPAL3, anticorps 2610511M17Rik, anticorps signal induced proliferation associated 1 like 3, anticorps signal-induced proliferation-associated 1 like 3, anticorps SIPA1L3, anticorps sipa1l3, anticorps Sipa1l3

Sujet: SIPA1L3 Antibody: Signal-induced proliferation associated-like protein 2 (SIPA1L3) is a member of the SIPA1 family of RapGAPs. SIPA1L3 was cloned as a novel molecular component of tight junctions and adherens junctions, suggesting that may function to balance Rap1 by counteracting RapGEFs. Recent studies of SIPA indicate that its deregulation can cause myeloproliferative stem cell disorders in mice and increased metastases in human cancers. Other studies suggest SIPA1L1 may play important roles in embryo development and control of cell proliferation. Based on the amount of homology between SIPA family members, it is possible that SIPA1L3 plays other roles development and cell proliferation.

ID gène: 23094

NCBI Accession: NP_055888

UniProt: O60292