NEUROD2 anticorps (AA 121-250) (AbBy Fluor® 750)

N° du produit ABIN5007466

L’anticorps Lapin Polyclonal anti-NEUROD2 a été validé pour WB, IF (cc) et IF (p). Il convient pour détecter NEUROD2 dans des échantillons de Humain.

Aperçu rapide pour NEUROD2 anticorps (AA 121-250) (AbBy Fluor® 750) (ABIN5007466)

Antigène: NEUROD2 (Neurogenic Differentiation 2 (NEUROD2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NEUROD2 est conjugé à/à la AbBy Fluor® 750

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-NEUROD2 anticorps (AbBy Fluor® 750)

Épitope: AA 121-250

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Neuro D2

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur NEUROD2

Antigène: NEUROD2 (Neurogenic Differentiation 2 (NEUROD2))

Autre désignation: Neuro D2

Sujet:

Synonyms: bHLHa1, Class A basic helix-loop-helix protein 1, class A basic helix loop helix protein 1, NDF2_HUMAN, NDR2, NDRF, Neuro-D2, NeuroD-related factor, NeuroD2, Neurogenic dferentiation factor 2, NDF2_HUMAN, neuroD related factor, NeuroD2, neurogenic basic helix loop helix protein, neurogenic dferentiation 2, Neurogenic dferentiation factor 2, neuronal dferentiation 2.

Background: Members of the myogenic determination family are basic helix-loop-helix (bHLH) proteins that can be separated into two classes, both of which work together to activate DNA transcription. Class A proteins include the ubiquitously expressed E-box binding factors, namely E2A, ITF-2 and HEB, while class B proteins, such as MyoD, myogenin and Neuro D (BETA2), are transiently expressed and exhibit a much more limited tissue distribution. Working in opposition to these positively acting factors are a specialized group of basic helix-loop-helix (bHLH) transcription factors that function as dominant negative regulators and are involved in cell lineage determination and differentiation. Neuro D2 (neurogenic differentiation 2), also known as NDRF, NEUROD2 or bHLHa1, is a 382 amino acid nuclear protein that contains one bHLH domain and functions to induce neurogenic differentiation, playing an important role in the maintenance and determination of cell fate.