SLITRK6 anticorps (C-Term)
Aperçu rapide pour SLITRK6 anticorps (C-Term) (ABIN500770)
Antigène
Voir toutes SLITRK6 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Specificité
- This antibody detects SLITRK6 at C-term. It is predicted to have no cross-reactivity to other Slitrk proteins.
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Réactivité croisée (Details)
- Species reactivity (tested):Human, mouse, rat
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Purification
- Peptide affinita chromatography
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Immunogène
- Slitrk6 antibody was raised against a 16 amino acid peptide from near the carboxy terminus of human Slitrk6.
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Isotype
- IgG
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Indications d'application
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ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Buffer
- PBS containing 0.02 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- SLITRK6 (SLIT and NTRK-Like Family, Member 6 (SLITRK6))
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Autre désignation
- SLITRK6
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Sujet
- SLIT and NTRK-like family 6 (Slitrk6) is a member a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains. Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the protein family. Slitrk6 expression has been observed in tissues such as tongue, lung, gastrointestinal tract, and pancreas. Like every other Slitrk protein except Slitrk1, overexpression of Slitrk6 inhibited neurite outgrowth in cultured neurons, suggesting that these proteins are involved in the control of neurite outgrowth. At least two isoforms of Slitrk6 are known to exisit.Synonyms: SLIT and NTRK-like protein 6
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ID gène
- 84189
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UniProt
- Q9H5Y7
Antigène
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