SPRED2 anticorps (Center)

N° du produit ABIN500800

Détail du produit anti-SPRED2 anticorps

Antigène: SPRED2 (Sprouty-Related, EVH1 Domain Containing 2 (SPRED2))

Épitope: Center

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SPRED2 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody detects SPRED2. It is predicted to have no cross-reactivity to Spred1 or Spred3.

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Peptide affinity chromatography

Immunogène: Spred2 antibody was raised against a 13 amino acid peptide near the center of the human Spred2.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur SPRED2

Antigène: SPRED2 (Sprouty-Related, EVH1 Domain Containing 2 (SPRED2))

Autre désignation: SPRED2 (SPRED2 Produits)

Synonymes: anticorps SPRED2, anticorps Xspred2, anticorps spred-2, anticorps Xtspred2, anticorps spred2, anticorps wu:fb93f08, anticorps zgc:77284, anticorps Spred-2, anticorps C79158, anticorps sprouty related EVH1 domain containing 2, anticorps sprouty related, EVH1 domain containing 2, anticorps sprouty-related, EVH1 domain containing 2b, anticorps sprouty-related, EVH1 domain containing 2, anticorps SPRED2, anticorps spred2, anticorps spred2b, anticorps Spred2

Sujet: Spred2 is a member of the Sprouty family, a group of proteins that act as negative regulators during development. Like Spred1, Spred2 acts by suppressing the phosphorylation and activation of Raf. The Spred proteins have also been implicated in the negative feedback regulation of FGF signaling in embryogenesis and angiogenesis. Further studies have shown that expression levels of Spred1 and Spred2 proteins are inversely correlated with the incidence of tumor invasion and metastasis in human hepatocellular carcinoma (HHC), suggesting that these proteins could be useful as prognostic factors and therapeutic targets in HCC. At least two isoforms of Spred2 are known to exist.Synonyms: MGC163164, Spred-2, Sprouty-related EVH1 domain containing 2

ID gène: 200734

NCBI Accession: NP_861449