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Stim2 anticorps (Center)

Stim2 Reactivité: Humain, Souris, Rat WB, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN500831
  • Antigène Voir toutes Stim2 Anticorps
    Stim2 (Stromal Interaction Molecule 2 (Stim2))
    Épitope
    • 10
    • 8
    • 7
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    Reactivité
    • 38
    • 14
    • 9
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 36
    • 1
    • 1
    Lapin
    Clonalité
    • 38
    Polyclonal
    Conjugué
    • 22
    • 5
    • 4
    • 3
    • 2
    • 2
    Cet anticorp Stim2 est non-conjugé
    Application
    • 34
    • 27
    • 19
    • 5
    • 4
    • 4
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificité
    This antibody detects STIM2 at center. It is predicted to have no cross-reactivity to STIM1.
    Réactivité croisée (Details)
    Species reactivity (tested):Human, mouse, rat
    Purification
    Peptide affinity chromatography
    Immunogène
    STIM2 antibody was raised against a 17 amino acid peptide from near the center of human STIM2.
    Isotype
    IgG
    Top Product
    Discover our top product Stim2 Anticorps primaire
  • Indications d'application
    ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Antigène
    Stim2 (Stromal Interaction Molecule 2 (Stim2))
    Autre désignation
    STIM2 (Stim2 Produits)
    Synonymes
    anticorps STIM2, anticorps stromal interaction molecule 2, anticorps STIM2, anticorps stim2, anticorps Stim2
    Sujet
    In T lymphocytes, the sole pathway for Ca++ entry following antigen-receptor binding is through store-operated Ca++-release-activated Ca++ (CRAC) channels. These channels are made up of the pore-forming subunit ORAI1 and the stromal interaction molecule 1 (STIM1), a protein that functions as a Ca++ sensor and activates the CRAC channels, migrating to the plasma membrane from endoplasmic reticulum (ER)-like sites which act as the Ca++ store. A related molecule, STIM2, acts to inhibit the STIM1-mediated store-operated Ca++ entry, and can form complexes with STIM1, suggesting they may play a coordinated role in controlling Ca++ entry. At least three isoforms of STIM2 are known to exist. This STIM2 antibody is predicted to have no cross-reactivity to STIM1.Synonyms: KIAA1482, Stromal interaction molecule 2
    ID gène
    57620
    NCBI Accession
    NP_065911
    Pathways
    TCR Signaling, BCR Signaling
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