TLR7 anticorps (Middle Region)

N° du produit ABIN500962

Cet anticorps Lapin Polyclonal détecte spécifiquement TLR7 dans WB, IF et EIA. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour TLR7 anticorps (Middle Region) (ABIN500962)

Antigène: TLR7 (Toll-Like Receptor 7 (TLR7))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TLR7 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Détail du produit anti-TLR7 anticorps

Épitope: Middle Region

Specificité: This antibody detects TLR7 at Center.

Réactivité croisée (Details): Species reactivity (tested):Human, mouse

Purification: Ion exchange chromatography

Immunogène: TLR7 antibody was raised against a peptide corresponding to 14 amino acids near the middle of mouse TLR7.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot: 0.5 to 2 μg/mL. Immunoflourescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur TLR7

Antigène: TLR7 (Toll-Like Receptor 7 (TLR7))

Autre désignation: TLR7

Sujet: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1-3). These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors (4,5). TLR7, like TLRs 3, 8, and 9, is localized in intracellular acidic compartments such as the phagolysosome (6) and will recognize some single-stranded RNA viruses such as vesicular stomatitis virus (VSV) and influenza virus (7). Activation of TLR7 by VSV results in stimulation of the immune response including IFN? secretion, suggesting the importance of TLR7 in virus recognition.Synonyms: Toll-like receptor 7

ID gène: 170743

NCBI Accession: NP_573474

Pathways: Signalisation TLR, Activation of Innate immune Response, Toll-Like Receptors Cascades