MLXIPL anticorps (AA 81-180) (AbBy Fluor® 750)

N° du produit ABIN5012474

Cet anticorps anti-MLXIPL est un anticorps Lapin Polyclonal détectant MLXIPL dans IF (cc) et IF (p). Adapté pour Rat.

Aperçu rapide pour MLXIPL anticorps (AA 81-180) (AbBy Fluor® 750) (ABIN5012474)

Antigène: MLXIPL (MLX Interacting Protein-Like (MLXIPL))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MLXIPL est conjugé à/à la AbBy Fluor® 750

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-MLXIPL anticorps (AbBy Fluor® 750)

Épitope: AA 81-180

Réactivité croisée: Rat

Homologie: Human,Mouse,Dog,Cow,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human WBSCR14/ChREBP

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur MLXIPL

Antigène: MLXIPL (MLX Interacting Protein-Like (MLXIPL))

Autre désignation: WBSCR14

Sujet:

Synonyms: ChREBP, bHLHd14, Carbohydrate responsive element binding protein, MIO, MLX interacting protein like, Mlx interactor, MLXIPL, MONDOB, WBSCR 14, WBSCR14, Williams Beuren syndrome chromosome region 14, Williams Beuren syndrome chromosome region 14 protein, WS basic helix loop helix leucine zipper protein, WS bHLH, MLXPL_HUMAN.

Background: ChREBP (Carbohydrate responsive element binding protein) is a transcription factor playing a critical role in the nutrient and hormonal regulation of genes encoding enzymes of glucose metabolism and lipogenesis pathways. It contains several domains including a nuclear localization signal (NLS) near the N-terminus, polyproline domains, a basic helix-loop-helix leucine zipper (b/HLH/Zip) and a leucine zipper like (zip-like) domain.ChREBP is ubiquitously detected in various tissues, with highest expression in liver, kidney and white and brown adipose tissue. Under basal conditions ChREBP is localized in the cytosol, translocating into the nucleus upon high glucose stimulation following its dephosphorylation of serine 196.

ID gène: 51085

Pathways: Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process