CUEDC2 anticorps (AA 100-280)

N° du produit ABIN5027122

L’anticorps anti-CUEDC2 Polyclonal Lapin est utilisé pour la détection de CUEDC2 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour CUEDC2 anticorps (AA 100-280) (ABIN5027122)

Antigène: CUEDC2 (CUE Domain Containing 2 (CUEDC2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CUEDC2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CUEDC2 anticorps

Épitope: AA 100-280

Purification: Protein A Chromatography

Immunogène: A partial length recombinant CUEDC2 protein (amino acids 100-280) was used as the immunogen for this antibody.

Isotype: IgG

Information d'application

Indications d'application: WB: 1-2 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Détails sur CUEDC2

Antigène: CUEDC2 (CUE Domain Containing 2 (CUEDC2))

Autre désignation: CUEDC2

Sujet: CUE domain-containing protein 2 commonly known as CUEDC2 is a 32 kDa protein having CUE Domain. It is involved in ubiquitin and proteasome-mediated degradation of progesterone receptor and estrogen receptor. It interacts with PRB isoform of progesterone receptor (PR) and modulates estrogen receptor (ER)-alpha protein stability through the ubiquitin-proteasome pathway. High level expression of CUEDC2 found in breast cancer tissue compared to normal adjacent tissue. It is found that CUEDC2 has some role in regulating IKK dephosphorylation by recruiting PP1.

Poids moléculaire: 30 kDa

ID gène: 79004

UniProt: Q9H467