DLL3 anticorps (AA 62-286)
Aperçu rapide pour DLL3 anticorps (AA 62-286) (ABIN5027148)
Antigène
Voir toutes DLL3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 62-286
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Purification
- Protein A Chromatography
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Immunogène
- A partial length recombinant Delta like 3 protein (amino acids 62-286) was used as the immunogen for this antibody.
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Isotype
- IgG
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Indications d'application
- WB: 2-4 μg/mL
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Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- PBS containing 0.05 % BSA, PH 7.4
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- DLL3 (delta Like Protein 3 (DLL3))
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Autre désignation
- Delta like 3
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Sujet
- Delta like 3 (DLL3) is a member of Delta/Serrate/Lag2 (DSL) ligands for Notch receptors and plays a role in Notch signaling. Out of Five DSL ligands, DLL3 is the most structurally divergent DSL ligand. DLL3 is expressed throughout the presomitic mesoderm and is localized to the rostral somatic compartments. Homozygous disruptions of Notch1 and DLL3 result in severe abnormalities in somitogenesis. Mutations in the human DLL3 homolog cause recessive skeletal abnormalities in spondylocostal dysostosis with a consistent pattern of abnormal segmentation.
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Poids moléculaire
- 65 kDa
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ID gène
- 10683
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UniProt
- Q9NYJ7
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Pathways
- Signalisation Notch
Antigène
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