DLL3 anticorps (AA 62-286)

N° du produit ABIN5027148

Détail du produit anti-DLL3 anticorps

Antigène: DLL3 (delta Like Protein 3 (DLL3))

Épitope: AA 62-286

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DLL3 est non-conjugé

Application: Western Blotting (WB)

Purification: Protein A Chromatography

Immunogène: A partial length recombinant Delta like 3 protein (amino acids 62-286) was used as the immunogen for this antibody.

Isotype: IgG

Information d'application

Indications d'application: WB: 2-4 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Détails sur DLL3

Antigène: DLL3 (delta Like Protein 3 (DLL3))

Autre désignation: Delta like 3 (DLL3 Produits)

Synonymes: anticorps SCDO1, anticorps pu, anticorps pudgy, anticorps delta like canonical Notch ligand 3, anticorps delta-like 3 (Drosophila), anticorps DLL3, anticorps Dll3

Sujet: Delta like 3 (DLL3) is a member of Delta/Serrate/Lag2 (DSL) ligands for Notch receptors and plays a role in Notch signaling. Out of Five DSL ligands, DLL3 is the most structurally divergent DSL ligand. DLL3 is expressed throughout the presomitic mesoderm and is localized to the rostral somatic compartments. Homozygous disruptions of Notch1 and DLL3 result in severe abnormalities in somitogenesis. Mutations in the human DLL3 homolog cause recessive skeletal abnormalities in spondylocostal dysostosis with a consistent pattern of abnormal segmentation.

Poids moléculaire: 65 kDa

ID gène: 10683

UniProt: Q9NYJ7

Pathways: Signalisation Notch